From method development to validation, our analytical chemistry experts can help quantitate and characterize a wide range of compounds to accelerate your drug development program.
Our state-of-the-art instrumentation include a High Resolution Orbitrap Mass Spectrometer, several triple quad LC-MS/MS systems, a Semi-Preparative High-Performance Liquid Chromatography (HPLC), a Gas Chromatography Mass Spectrometry (GC-MS/FID System) system, and an Ultrahigh Pressure Liquid Chromatography (UPLC) equipped with a Charged Aerosol Detector (CAD), Diode Array Detector (DAD), and Refractive Index (RI) detector.
What Analytical Services Do We Offer?
Emery Pharma Can Help
with Your Analytical Needs
Emery Pharma is a full-service contract research laboratory, specializing in supporting preclinical drug development, including analytical, bioanalytical solutions, microbiology & cell biology services, drug and impurity characterization, and general R&D and cGMP/GLP support. Emery Pharma provides exceptional analytical solutions for our Clients’ toughest R&D challenges and tailors those solutions to fit each Client’s unique needs.
Biologics Analytical Characterization
Emery Pharma has the required expertise and facilities to routinely characterize a wide variety of structural and chemical qualities in biologic compounds. We offer an extensive array of biologics characterization services, including de novo method development and validation. The identity is determined through liquid chromatography – mass spectrometry (LC-MS) analysis of both the intact molecule and a proteolytic digest. The purity of the drug substance/product can be assessed with respect to the extent of aggregation via Size Exclusion Chromatography (SEC). Whereas the purity with respect to charge variants is determined through Ion Exchange Chromatography (IEX).
Liquid Chromatography Mass Spectrometry (LC-MS) is an analytical chemistry laboratory technique that can be used for identification, quantification, and mass analysis of samples and materials. Our tandem LC-MS (LC-MS/MS) is especially powerful in detecting and quantifying a variety of molecules.
Nuclear Magnetic Resonance (NMR) Spectroscopy is an analytical chemistry laboratory technique used to look at the chemical environments of a selected nucleus on a molecular level. From basic 1H NMR analysis with minimal processing, to complete structure analysis (including a full range of 2D NMR) and interpretations.
We offer bioanalytical services with state-of-the-art method development, transfer, validation, and sample and metabolite analysis. We have proprietary assays and assay development for biological samples analysis in blood plasma, serum, tissue, urine and feces, as well as raw materials, formulated products and environmental samples.
Metabolomics is broadly defined as the comprehensive measurement of all metabolites and low-molecular-weight molecules in a biological sample. We have a comprehensive platform with advanced instruments including UPLC-HR MS, GC-MS, UPLC-QqQ-MS/MS, and NMR to address all forms of untargeted and targeted metabolomics needs.
High-performance liquid chromatography (HPLC) is a power-house analytical technique used for separation, identification, and quantitation of component(s) in a mixture. We offer a wide range of HPLC/UPLC techniques with variety of detectors for different analytes: mass spectrometry (LC-MS), UV-Vis (VWD, DAD), charged aerosol detectors (CAD), and refractive index (RI) – covering the gamut of HPLC/UPLC applications.
Proteomics is the study of the proteome, the entire set of proteins produced by a living system. It involves identification of proteins, investigation of protein abundances, the variations, and modifications therein, as well as insight into interacting partners and networks.
Medicinal Chemistry Support
From strategic planning, to hit evaluation and validation, to lead optimization and pre-clinical development, we support diverse therapeutic areas. We're experienced in developing drugs from original concept all the way to FDA approval.
Gas Chromatography (GC) is used for analyzing compounds that are volatile or can be vaporized at higher temperatures without decomposition, either in their native form (e.g., odorous oils, organic solvents) or converted to a volatile derivative (e.g., alcohols, amines, carboxylic acids via silylation, methylation, etc.). We utilize both liquid injection and thermal desorption methods (including SPME) and USP/FDA Headspace sampling, as well as derivatization poorly volatile analytes.