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The Meso Scale Discovery (MSD) platform has become a cornerstone technology for both large molecule pharmacokinetic (PK) assays and pharmacodynamic (PD) biomarker assessments. Its electrochemiluminescence detection technology offers high sensitivity, broad dynamic range, low sample volume requirements, and multiplexing capabilities,…
Introduction Anti-drug antibody (ADA) assays are critical for evaluating drug safety and are required throughout pre‑clinical and clinical development. In a standard bridging ADA assay, anti-drug antibodies in the sample “link” a capture reagent and a detection reagent, forming a…
Background Biomarker assessment is a critical component of pharmaceutical drug development, providing insight into how a therapeutic candidate affects biological systems and whether it is achieving its intended mechanism of action. Biomarkers can be selected through a review of published…
Validation vs Cross Validation Monoclonal antibody-based drugs have revolutionized the treatment of cancer and autoimmune diseases. Before a new antibody drug can enter human clinical trial, a method must be developed to enable the detection and quantitation of the drug…
The detection and quantitation of proteins, whether therapeutic agents or endogenous biomarkers, plays a central role in drug development and biopharmaceutical research. While small molecules have historically dominated the pharmaceutical landscape, large molecule therapeutics such as monoclonal antibodies have grown…
The COVID-19 pandemic kickstarted a renewed interest in antiviral development within the pharmaceutical and personal care industries. But even before the COVID-19 pandemic viral infections have been a major public health burden, with children in developed countries alone experiencing an…
When people hear the words “antibiotic”, they often imagine a drug killing harmful bacteria when the two come into contact. But due to factors such as drug toxicity, host metabolism, etc. it is not possible to maintain continuous exposure of…
Antimicrobial resistance is a growing concern in healthcare and pharmaceutical research, making robust antimicrobial testing crucial for developing effective therapies. At Emery Pharma, we specialize in antimicrobial testing, including Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC), and Minimum Fungicidal…
Humans have been weaving textiles and fashioning clothing from fabrics for thousands of years, but one of the great challenges since the dawn of civilization has been the degradation and fouling of clothing from microorganisms. Bacteria and fungi from the…
Cancer is a complex disease that requires a multifaceted approach to treatment in order to prevent regression. In the past, traditional treatments in oncology have consisted of small molecule cytotoxic drugs (alkylating agents, antimetabolites, etc.), and recently, more targeted therapies…